What are the effects of chronic kidney disease on the body?

What are the effects of chronic kidney disease on the body? So in simple terms the job of the kidneys is to clean the blood and it produces the waste product which we know of as urine and kidneys also play an important role in controlling blood pressure. Therefore if the kidneys don't work properly people tend to develop high blood pressure. Equally, the blood is dirty because the kidneys are not cleaning it properly, and so as the level of toxins builds up in the blood, people can start to feel sick, itchy, as phosphate is deposited in their skin, and tired because they become progressively anemic. Equally, if you think if you are unable to produce urine or unable to produce enough urine, then you develop symptoms of fluid retention. Fluid in the body follows gravity, so people with advanced kidney impairment as they walk around will find they develop ankle swelling, but then if they lie flat in bed at night, they may notice that they become short of breath because the fluid tracks up from their legs into the bottom of their lungs. Then they wake up in the morning, they don't have ankle swelling but they stand up during the day and the ankle swelling comes back.