Appetite Regulation MechanismsDigestive Process Influencerstype 2 diabetesGLP-1 injectionsGLP-1 treatmentsbraingut
What are GLP-1 inhibitors and how do they work?
Dr Sheharyar Quraishi, Consultant Endocrinologist and Diabetologist talk about GLP-1 inhibitors. He explains where these medicines come from and what actions they do. He explains how they affect the link between the gut and the brain and influence appetite and also transit of food though digestion.
Transcript (auto-generated)
This transcript was generated automatically and may contain errors.
GLP-1 injections are peptides. They're gut hormone peptide molecules. They're synthesized in the laboratory. In patients with diabetes, the feedback loop from the bowel to the brain is impaired, which essentially means that most of the patients with type 2 diabetes would have higher body weights because they would have more higher, higher appetites. And they would feel less full compared to somebody who don't have diabetes. So GLP-1 treatments of peptides, which are designed to close that loop in which the gut can speak to the brain and eventually lead to decreasing the amount of the appetite and also increasing amount of satiety and slowing the transit of the food through the gut that would eventually lead to the weight loss.
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