What you might expect on starting SGLT-2 inhibitors.

Two inhibitors would lead to increased urination, which would mean that you pass a lot more urine that you would otherwise would. The other thing to be conscious of developing fungal rash in the genital area, which is a reason for discontinuation of the SGLT2 treatment, the third thing we would notice is a 20% change into the blood pressure, which means if patients also have hypertension associated with diabetes, then there is a benefit of reduction into the antihypertensive therapy, which essentially is a side effect of SGLT2s working as diuretics and leading to a lot of fluid loss because of the mechanism of action and how they work.