How can we achieve weight loss of 25% or more?

How can we achieve a weight loss of 25%? So to achieve this degree of weight loss, we'll need some sort of surgical intervention. Previously I've spoken to you about what can be achieved through lifestyle changes, changes, around 5% weight loss. If you add medications to this, you can achieve around maybe 10% weight loss. If you add balloons or endoscopic treatments, you can maybe achieve 10-15% weight loss. But to achieve a 25% or higher weight loss, at our current knowledge in the field of weight loss, this degree of weight loss would require some sort of surgical intervention. We have some very effective weight loss operations which will achieve this degree of weight loss and maintain this weight loss long term.